Book Hotels in South San Diego, CA

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Top South San Diego hotels

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr, National City, CA
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $158 total per night from Oct 13 to Oct 14
$158 total
Oct 13 - Oct 14
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this eco-certified hotel. Bring the family and enjoy the mini golf, children's pool, and kid-friendly ...
"Thanks"

Reviewed on Oct 1, 2025

Opens in a new windowBest Western Plus Marina Gateway Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$296 nightly
The price is $343 total per night from Oct 10 to Oct 11
$343 total
Oct 10 - Oct 11
Total with taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
"The staff was very helpful and accommodating whenever I needed something they were able to help me right away and had a quick response if I needed to have anything delivered to the room or any other questions I had"

Reviewed on Oct 6, 2025

Opens in a new windowManchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $277 total per night from Oct 31 to Nov 1
$277 total
Oct 31 - Nov 1
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
"Clean room"

Reviewed on Oct 1, 2025

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Oct 13 to Oct 14
$138 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Room was clean and modern. Bed comfy. Was noisy beside the highway. Pool are very underwhelming."

Reviewed on Oct 2, 2025

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Oct 13 to Oct 14
$139 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also offered.
"Old-school hotel but good central location."

Reviewed on Oct 2, 2025

Opens in a new windowPalihotel San Diego Gaslamp Quarter
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $205 total per night from Oct 12 to Oct 13
$205 total
Oct 12 - Oct 13
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and ...
"First of all, fantastic location. Across the street from the water, another restaurants all around. 5 minute walk to the USS Midway museum. If you like to walk, this is an awesome location. We walked to the Gaslamp, Little Italy, Petco Park, and the convention center. An Uber ride to almost anywhere ..."

Reviewed on Oct 6, 2025

Opens in a new windowWyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
$110 nightly
The price is $126 total per night from Oct 8 to Oct 9
$126 total
Oct 8 - Oct 9
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"Location"

Reviewed on Oct 1, 2025

Opens in a new windowHandlery Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Oct 13 to Oct 14
$144 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Shopping options are great, we’ve never used the pool before."

Reviewed on Oct 4, 2025

Opens in a new windowHilton San Diego Mission Valley
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Oct 8 to Oct 9
$113 total
Oct 8 - Oct 9
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
"I appreciated how close it is to SDSU."

Reviewed on Oct 5, 2025

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler

The Rambler

225 Bay Blvd, Chula Vista, CA
$99 nightly
The price is $115 total per night from Oct 8 to Oct 9
$115 total
Oct 8 - Oct 9
Total with taxes and fees
9/10 Wonderful! (1,947 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"The staff was very helpful and accommodating whenever I needed something they were able to help me right away and had a quick response if I needed to have anything delivered to the room or any other questions I had"
A verified traveler from Modesto stayed at Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego

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